The Pathology Atlas contains mRNA and protein expression data from 17 different forms of human cancer. Correlation analyses based on mRNA expression levels 

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This reaction is thought to have regulatory importance, since Ins (3,4,5,6)P4 is an inhibitor of plasma membrane Ca 2+-activated Cl - channels, while Ins (1,3,4,5,6)P5 is not. Breast cancer is the most common cancer among women. Although the breast cancer mortality rates have fallen over the past few decades – thanks to early detection and treatment improvements – the disease remains the second leading cause of cancer death in females. 150517452{itpk1_enst00000556603}, 147474316{itpk1_enst00000555495}, 104254008{itpk1_enst00000354313} Tissue distribution This section displays the distribution of mutated samples and tissue types (top 5).

Itpk1 cancer

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ITPK1 (inositol-tetrakisphosphate 1-kinase) Non-annotated gene. Preliminary data : if you are an author. Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 4 ] magnesium ion binding inositol tetrakisphosphate 6-kinase activity catalytic activity ATP binding cytoplasm cytosol signal transduction blood coagulation apical plasma 2014-12-01 This gene does not have a cancer hallmark. You can see more information about hallmarks. COSMIC gene ITPKB (COSG226) Genomic coordinates 1:226631690..226739175 (negative strand) Synonyms IP3-3KB, IP3KB, CCDS1555.1, P27987, ENSG00000143772.9, NM_002221.3, NP_002212 COSMIC-3D No protein structures Kinase that can phosphorylate various inositol polyphosphate such as Ins (3,4,5,6)P4 or Ins (1,3,4)P3. Phosphorylates Ins (3,4,5,6)P4 at position 1 to form Ins (1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins (3,4,5,6)P4 is an inhibitor of plasma membrane Ca 2+-activated Cl - channels, while Ins (1,3,4,5,6)P5 is not.

CGAP: ITPK1 : Familial Cancer Database: ITPK1 * This gene is included in those cancer gene databases.. Oncogene 1.

Whether colon cancer runs in your family or you’re interested in learning about health conditions as part of an effort to improve your well-being, it’s important to understand this type of cancer. According to the American Cancer Society, a

4C), which confirmed that ITPK1 can use I(3)P 1 both in vitro and in vivo. Immune Thrombocytopenia. I. What every physician needs to know. Immune Thrombocytopenia (ITP) in the past has been called Idiopathic Thrombocytopenia Purpura and Immune Thrombocytopenic Purpura.

ITPK1 is not prognostic in breast cancer Alive (n=923) Dead (n=152) Female (n=1063) Male (n=12) Stage: i (n=89) ia (n=86) ib (n=5) ii (n=6) iia (n=352) iib (n=251) iii (n=2) iiia (n=153) iiib (n=25) iiic (n=63) iv (n=20) n/a (n=11) x (n=12)

Itpk1 cancer

Preliminary data : if you are an author. Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 4 ] magnesium ion binding inositol tetrakisphosphate 6-kinase activity catalytic activity ATP binding cytoplasm cytosol signal transduction blood coagulation apical plasma ITPK1 mutation reduces labeling of InsP 6 by 50%, with concomitant accumulation of d / l ‐Ins(3,4,5,6)P 4, but because it does so without affecting the level of Ins(1,3,4,5,6)P 5 (Figures 5a and S6a) suggests that ITPK1 probably does not act as an Ins(1,3,4,5,6)P 5 1‐phosphatase. Kinase that can phosphorylate various inositol polyphosphate such as Ins (3,4,5,6)P4 or Ins (1,3,4)P3. Phosphorylates Ins (3,4,5,6)P4 at position 1 to form Ins (1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins (3,4,5,6)P4 is an inhibitor of plasma membrane Ca 2+-activated Cl - channels, while Ins (1,3,4,5,6)P5 is not.

Blcap, bladder cancer associated protein, 1142, 31.93, 31.22, 30.05, 31.07, 6203 Itpk1, inositol 1,3,4-triphosphate 5/6 kinase, 2396, 37.96, 27.55, 42.27, 35.93  63, U-CAN, Uppsala Umeå Comprehensive Cancer Consortium, Sweden ITPK1, inositol-tetrakisphosphate 1-kise [Source:HGNC Symbol;Acc:6177], 0.4082  Cancer susceptibility candidate 1 OS=Rattus norvegicus GN=Casc1 PE=2 SV=1 Protein Itpk1 (Fragment) OS=Rattus norvegicus GN=Itpk1 PE=4 SV=2  Uncharacterized protein (Fragment) OS=Macaca mulatta GN=ITPK1 PE=4 in breast cancer gene 1 protein OS=Macaca mulatta GN=KIAA1967 PE=2 SV=1  för ett annat kinas som kallas ITPK1 , vilket är ett inositol 1, 3, 4-trisfosfat 5/6-kinas och inte I de flesta fall orsakar ITP3K-uttryck att cancer blir mer aggressiv. SP4, PLEKHA7, ITPK1 / C14orf109 och regionerna 10p11.23, 10q11.21, 6p23 och Ökade risker för cancer för släktingar till bröstcancerfall med mycket tidig  ITP 1/1863 - ITPK 1/1864 - ITPS 1/1865 - ITP (olika betydelser) 1/1866 - ITRE Guilds 11/15068 - International Agency for Research on Cancer 11/15069  ITPK1 : Inositol 1, 3, 4-Triphosphate 5/6 Kinase ; NM_014216.3; fw: IndexTerm TP73 : Tumor Protein p73 ; NM_005427.2; NM_001126240.1,  som ATP6V1B2, GRM7, SP4, PLEKHA7, ITPK1 / C14orf109 och regioner 10p11.23, 10q11.21, 6p23 och 2q22.1 (tabellerna 5 och 6 och kompletterande filer) . Three additional loci are linked to the SLC24A3, ITPK1 and GJA1 genes, which all have a function in cellular ion homeostasis. More unexpectedly, many genes  Cancer, hematologisk utveckling, immunologiska och inflammatoriska Dessutom finns cg05284742 relaterad till NO 2- exponering i ITPK1; denna gen  This is NOT a known cancer gene. It is not found in the Cancer Gene Census . Curated gene. This is NOT an expert curated gene .
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Itpk1 cancer

doi: 10.3892/ol.2019.10124. Epub 2019 Mar 8. Five-long non-coding RNA risk score system for the effective prediction of gastric cancer patient survival. Download Citation | On Jan 1, 2016, Yixing Zhou and others published ITPK1 (Inositol Tetrakisphosphate 1-Kinase) | Find, read and cite all the research you need on ResearchGate CGAP: ITPK1 : Familial Cancer Database: ITPK1 * This gene is included in those cancer gene databases.. Oncogene 1.

©2014 AACR . In this study, we investigated the potential role of HIF2α in regulating RCC susceptibility to natural killer (NK) cell–mediated killing. We demonstrated that the RCC cell line 786-0 with mutated VHL was resistant to NK-mediated lysis as compared with the VHL-corrected cell line (WT7).
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Expression of ITPK1 in human tissue. Overview of the antibody staining with HPA055230 in immunohistochemistry

blood atlas cell lineages. b-cells dendritic cells granulocytes ITPK1 is the kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. It may also act as an isomerase that interconverts the inositol tetraphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of A ITPK1 participant CRISPR screens (93 hits / 997 screens). Download Results .


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Rabbit Polyclonal ITPK1 antibody [N3C3]. Validated in WB, ICC/IF. Tested in Human, Mouse. Cited in 1 reference(s).

Immune Thrombocytopenia (ITP) in the past has been called Idiopathic Thrombocytopenia Purpura and Immune Thrombocytopenic Purpura. The risk score system based on the green module [including ITPK1 antisense RNA 1 (ITPK1-AS1), KCNQ1 downstream neighbor (KCNQ1DN), long intergenic non-protein coding RNA 167 (LINC00167), LINC00173 and LINC00307] was the more efficient at predicting risk compared with those based on the turquoise, or the green + turquoise modules. ITPK1 (inositol-tetrakisphosphate 1-kinase) Non-annotated gene. Preliminary data : if you are an author. Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 4 ] magnesium ion binding inositol tetrakisphosphate 6-kinase activity catalytic activity ATP binding cytoplasm cytosol signal transduction blood coagulation apical plasma 2014-12-01 This gene does not have a cancer hallmark. You can see more information about hallmarks. COSMIC gene ITPKB (COSG226) Genomic coordinates 1:226631690..226739175 (negative strand) Synonyms IP3-3KB, IP3KB, CCDS1555.1, P27987, ENSG00000143772.9, NM_002221.3, NP_002212 COSMIC-3D No protein structures Kinase that can phosphorylate various inositol polyphosphate such as Ins (3,4,5,6)P4 or Ins (1,3,4)P3.

Lung cancer is a leading type of cancer — and a leading killer — in the United States every year. The good news is many cases of lung cancer are believed to be preventable, as an estimated 90% of lung cancer cases are caused by active smoki

Showing subcellular location of ITPK1. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. 2000-05-01 · itpk1_arath

This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Summary of ITPK1 expression in human tissue. Moderate cytoplasmic positivity was displayed in intestinal glands, gall bladder, thyroid, renal tubules, granular layer of cerebellum and heart myocytes.

High. N. -0.02 0.76 2.11. 56 KDM3B. 1 Serologically defined breast cancer antigen 84 1 Lung cancer candidate 1 Inositol 1,3,4-triphosphate 5/6 kinase. ITPK1. Hs.6453. AA010675.